Dozens of studies performed on cynomolgus monkeys, bonobos, chimps, and baboons have demonstrated that having low social status–even while maintaining the exact same diet at high social status individuals–induces impaired fertility in primates.
Human models, while approximations, do not differ. In some, a simple progesterone-dampening effect occurs, in others the levels decrease precipitously, in most cortisol levels skyrocket, but in general a wide spectrum of reproductive disorders- from hormone deficiency to full-blown long-term amenorrheic infertility- follow from psychological stress.
This is something about which I have written before, and it’s a serious problem, causing not just outright and obvious infertility but also sneakily impaired and sub-optimal fertility all across the country.
Pysychological stress wreaks all sorts of havoc on the body. Most importantly, cortisol levels rise, and the body’s inflammatory and immune responses become impaired. Blood sugar levels rise, and insulin levels rise, too. When these things happen, healing cannot occur, and tissues become progressively damaged with time. This applies to reproductive tissues as much as it does to the rest of them. Hypercortisolemia is good for nobody.
Several hormone responses also occur. Three of the primary ones are as follows:
1) As I mentioned, due to elevated cortisol levels, insulin levels may rise, and testosterone levels rise right alongside it. This is because insulin directly stimulates testosterone production in the ovaries. This is bad for reproduction because a proper balance between testosterone and female balance needs to be maintained in order for proper reproductive signalling and tissue development to occur. One particularly potent way in which this imbalance often hurts women is in the hormone condition Poly Cystic Ovarian Syndrome. It is not the only thing that contributes to PCOS– definitely not– but it can play a big time role in it. For more on stress and PCOS (and overcoming PCOS!), check out the book I wrote.
2) Moreover, another effect that may occur as a result of stress is an increase in production of DHEA-S, a hormone produced in the stress glands. DHEA-S is, like all other hormones, an important and very healthful hormone in proper balance. But if the stress glands are in overdrive, they might over-produce everything, including DHEA-S. This is detrimental, because DHEA-S is also a classically male sex hormone, and it plays a role similar to testosterone in PCOS. DHEA-S in excess blocks estrogen signaling, interferes with LH and FSH signaling, and also increases hormonal acne. DHEA-S can play a role in both type I and type II PCOS.
3) Finally, the brain, via the hypothalamus, sometimes turns off pituitary activity in response to stress. This often leads to a cessation of LH and FSH signaling–the two primary pituitary signalling molecules–which in turn decreases levels of estrogen and progesterone in the blood. Recall that reduced progesterone levels are one of the primary markers of reproductive distress in primate studies. Prolactin levels may also decrease. These facts make it impossible both to ovulate and to menstruate.
*Graphic extracted from PCOS Unlocked: The Manual.
These three categories– testosterone elevation, DHEA-S elevation, and pituitary decreases may occur differently in all women. And there are a wide variety of other, more subtle, hormonal responses that also occur, especially when considered in conjunction with all of the other bodily stress that follows from psychological woes.
All that being said, STRESS IS BAD. We know some of the reasons why, as I’ve explained above. Others likely exist. Even if you don’t have infertility problems, you may have hormone imbalances or deficiencies, and those can be just as insidious. Eat right, sleep right, live well, breath deeply. Repeat.
Stress is a significant problem for women’s health, and particularly women’s hormonal health. This is manifested in a wide array of problems, but also most predominantly these days in the condition PCOS, or Poly Cystic Ovarian Syndrome.
You can read more about stress and it’s interplay with cysts, as well as how to overcome it all, in my guide, PCOS Unlocked: The Manual.